GeneCopoeia Genome-CRISP CRISPR products and services

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GeneCopoeia’s Genome-CRISP CRISPR-Cas9 products and services are designed to provide a complete solution for precision RNA-guided genome editing.

The company provides over 45,000 human, mouse and rat genes to knock out using CRISPR. It also offers HDR donor cloning vectors and custom HDR donor construction, for CRISPR genome editing applications in which homolgous recombination will be used.

Premade Cas9-expressing stable cell lines are suitable for sgRNA library screening and other high-throughput CRISPR-Cas9 applications. Users can meanwhile create knock-ins of virtually any DNA fragment using the company’s Safe Harbor knock-in kits for human AAVS1 and mouse ROSA26.

The IndelCheck insertion/deletion detection system is a complete system for pre-validation of sgRNAs and screening for genome modifications. It includes a T7 Endonuclease I assay kit and a target site PCR kit. Target site-specific PCR primers are optional.

Users can choose from seven pre-made, pathway-specific, lentiviral-based sgRNA libraries in a variety of formats. Custom libraries are also available on request.

Finally, VividFISH chromosome probes for fluorescence in situ hybridisation (FISH) will help users with their genome editing workflow in cultured mammalian cell lines.

Originally published here.